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Enevia Health, LLC
30 N Gould Ste N, Sheridan, WY 82801, USA
- info@eneviahealth.com
What is the relationship between autism and folate?
There is a disorder called Cerebral Folate Deficiency (CFD) which in many cases have symptoms compatible with autism, such as developmental regression, speech problems, seizures, agitation and insomnia, hypotonia, psychomotor retardation, epilepsy, gait disorders, ataxia...
CFD is caused, in some cases, by folate receptor alpha antibodies (FRAAs) that block folate from entering the brain. CFD in many cases can be treated with folinic acid. When folinic acid is administered, active metabolic levels of folate increase and clinical improvements occur in these patients.
Folinic acid is a type of folic acid that can enter the brain through a different channel than the more common folic acids.
The doctor. Richard Frye noted a very high prevalence of Folate Receptor Antibodies (FRAA) in the blood of children with ASD, and that some had low levels of folate in their central nervous system, similar to children with CFD.
Dr. Frye and his group published the results of a multi-year study showing that folinic acid improves speech, language, and other symptoms in children with autism (improvement in verbal communication and other behaviors such as life skills daily, irritability, stereotyped behavior and hyperactivity).
Link to the study: https://www.nature.com/articles/mp2011175
The study also showed that the FRAA biomarker could help predict who will respond to folinic acid treatment.
After more than 1 year coordinating with SYNLAB and ILLIAD NEUROSCIENCE, we finally have the opportunity to do the FRAT®️ Test in Spain and EU countries, easily and without traveling to the US.
The complexity of this test lies in the temperature control of the samples and in the shipment so that they arrive at the laboratory in the US in perfect condition. To reduce the price of transport with controlled temperature we have agreed with Synlab group shipments. Synlab Spain is in charge of drawing the blood and sending it to the US, guaranteeing the stability of the samples.
Purchasing process: Buy the test here and send an e-mail to make an appointment at Synlab to do the extraction in citaprevia.empresas@synlab.es
Detail in the e-mail:
- That you are members of Enevia Health.
- FRAT test purchase order number (when making the purchase on the website you will receive an e-mail confirming the purchase and the order number).
If your doctor has prescribed the FRAT, take the form with you, signed by him on the day of the blood draw. If a doctor has not prescribed it, ask us for the form and we will send it to you, signed by an Enevia doctor.
Remember: You cannot take folic acid supplements or food fortified with folic acid 72 hours before the extraction, it is not necessary to fast but it is recommended.
Very important!!! when performing the extraction, the laboratory will give you a receipt with an access code to enter the Synlab website and see the results, DON'T FORGET TO ASK FOR THE RECOVERY!!!
Synlab will accumulate the frozen samples at -80°C and when they have 10, they will send them to the US laboratory, in this way there is no need to coordinate a specific extraction day for the group.
Keep in mind that the date on which the shipment will leave for the US cannot be guaranteed, since it will depend on how long it takes to collect 10 samples.
Samples frozen at -80°C have a viability of years, so there is no danger of spoilage.
➡️ Those people who agree to do this test have to take into account its particularities.
In PDF-1 you can access information on the scientific basis of FRAT, in PDF-2 a list of questions and answers and in PDF-3 you will find more information on the improvement of folinic acid and communication.
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30 N Gould Ste N, Sheridan, WY 82801, USA
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*Our purpose is informational only, it is not intended to be a substitute for medical advice, diagnosis or treatment.
This plan is exclusive for people who are responsible for or suffer from some neurodevelopmental pathology such as (TEA, ADD, ADHD, OCD, SLI and other learning disorders, as well as Rett syndrome, Tourette syndrome, PANS, PANDAS , LYME…
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