Histamine intolerance test.
Histamine is a molecule derived from an essential amino acid, histimine, and is produced by decarboxylation thanks to the enzyme L-histidine decarboxylase. Histamine has many physiological and pathophysiological functions: it participates in the regulation of local circulation, in capillary hypermeability, in the contraction and relaxation of smooth muscle and blood vessels, in the secretion of hydrochloric acid in the stomach, in the responses of immediate hypersensitivity, in allergic processes, in inflammatory processes as part of an immune response to external pathogens, in tissue healing and its action as a neurotransmitter of the central nervous system has also been identified. One of the main functions of endogenous histamine is the participation in the immune system, in allergic reactions.
The second way of obtaining histamine is from food and it is the one that can represent more problems, since its regulation depends on the individual himself. If there is any alteration in its metabolism and normal concentrations of histamine in the blood (50-70 mg/l) are not maintained, the free circulation of this amine in high concentrations triggers unwanted effects, including migraine, fibromyalgia, asthenia and atopy.
Diet greatly influences health and mood. If you frequently experience discomfort such as nasal congestion, migraines, constipation, sleep disturbances, fatigue, skin rashes, irritability, and even more severe conditions such as irritable bowel syndrome or arthritis, you may be suffering from histamine intolerance and your specialist will advise you. a low histamine diet.