Intestinal Permeability Zonulina in feces, Calderón

A increased intestinal permeability It is due to alterations of the villi and microvilli that are part of the intestinal epithelium composed of a monocellular layer and, above all, to alterations of the intercellular spaces of that intestinal epithelium. This alteration causes the massive entry of bacterial or food antigens, pathogens, toxins and semi-digested food molecules (peptides, lipids, polysaccharides,...)

The repeated introduction of food antigens through the intestinal mucosa could be responsible for immune responses mediated by IgG or IgE antibodies. resulting in a chronic inflammatory reaction that can explain different pathologies: various inflammatory diseases, autoimmune diseases, allergies, etc., which can be clinically manifested by very varied symptoms: eczema, asthma, colitis, joint and/or muscle pain, headaches, abdominal swelling, diarrhoea, Crohn's, halitosis, etc.