It is a proprietary diagnostic blood test that detects antibodies to folate receptor alpha (aRF). The FRAT is an important tool for evaluating your child's neurological health.

𝗖𝘂𝗮𝗖𝘂𝗮 𝗲𝘀 𝗹𝗮 𝗱𝗲 𝗲𝘀𝘁𝗼𝘀 𝗮𝗻𝘁𝗶𝗰𝘂𝗲𝗿𝗽𝗼𝘀 𝗾𝘂𝗲 𝘀𝗲 𝗱𝗶𝗿𝗶𝗴𝗲𝗻 𝗮𝗹 𝗿𝗲𝗰𝗲𝗽𝘁𝗼𝗿 𝗱𝗲 𝗮𝗹𝗳𝗮 (𝗙𝗥𝗮)?

These antibodies, which are either blocking antibodies, binding antibodies, or a combination of the two, prevent adequate folate uptake in critically important tissues such as the brain. Folate deficiency in the brain is common in children with autism.

𝗤𝘂𝗲 𝗶𝗺𝗽𝗹𝗶𝗰𝗮𝗰𝗶𝗼𝗻𝗲𝘀 𝘁𝗶𝗲𝗻𝗲𝗻 𝗮𝗻𝘁𝗶𝗰𝘂𝗲𝗿𝗽𝗼𝘀 𝗿𝗲𝗰𝗲𝗽𝘁𝗼𝗿𝗲𝘀 𝗱𝗲 𝗳𝗼𝗹𝗮𝘁𝗼 𝗲𝗻 𝗹𝗮 𝘀𝗮𝗹𝘂𝗱 𝗻𝗲𝘂𝗿𝗼𝗹𝗼 𝗻𝗲𝘂𝗿𝗼𝗹𝗼 𝗻𝗲𝘂𝗿𝗼𝗹𝗼 𝗻𝗲𝘂𝗿𝗼𝗹𝗼 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱 𝘀𝗮𝗹𝘂𝗱

The presence of folate receptor antibodies suggests that folate (vitamin B9), which is an essential vitamin, is not properly transported to the brain, possibly contributing to neurodevelopmental disorders such as autism.

𝗘𝘀 𝗲𝗹 𝗺𝘂𝘆 𝗶𝗺𝗽𝗼𝗿𝘁𝗮𝗻𝘁𝗲 𝗽𝗮𝗿𝗮 𝗹𝗮 𝗳𝘂𝗻𝗰𝗶𝗼 𝗳𝘂𝗻𝗰𝗶𝗼 𝗻𝗲𝘂𝗿𝗼𝗹𝗼 𝗻𝗲𝘂𝗿𝗼𝗹𝗼 𝗮𝗱𝗲𝗰𝘂𝗮𝗱𝗮?

Yes, unequivocally. Folate, (vitamin B9), is essential for normal growth and development in humans. It is also necessary to maintain a healthy nervous system, which contributes to normal nerve maintenance and proper brain function. Lack of adequate folate levels has been linked to various neurological disorders such as:
• Cerebral folate deficiency
• Autism spectrum disorders
• Neural tube defects
• Pregnancy complications such as miscarriage and prematurity

𝗦𝗲 𝗵𝗮𝗻 𝗮𝗻𝘁𝗶𝗰𝘂𝗲𝗿𝗽𝗼𝘀 𝗿𝗲𝗰𝗲𝗽𝘁𝗼𝗿𝗲𝘀 𝗱𝗲 𝗳𝗼𝗹𝗮𝘁𝗼 𝗲𝗻 𝗻𝗶𝗻̃𝗼𝘀 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰𝗮𝗱𝗼𝘀 𝗰𝗼𝗻 𝘁𝗿𝗮𝘀𝘁𝗼𝗿𝗻𝗼𝘀 𝗱𝗲𝗹 𝗮𝘂𝘁𝗶𝘀𝘁𝗮?

Yes, a large percentage of children with autism have been found to have these antibodies.

𝗖𝗼́𝗺𝗼 𝗺𝗲 𝗮𝘆𝘂𝗱𝗮 𝗙𝗥𝗔𝗧?

FRAT will confirm the presence of these antibodies against folate receptor alpha, suggesting that not enough folate is being transported to the brain.
Folate insufficiency can often be corrected by administering active folate metabolites that bypass the blocked/binding receptors. Consult your doctor for more information on available therapeutic approaches.

𝗘𝘅𝗶𝘀𝘁𝗲 𝗲𝘃𝗶𝗱𝗲𝗻𝗰𝗶𝗮 𝗰𝗶𝗲𝗻𝘁𝗶 𝗾𝘂𝗲 𝗿𝗲𝘀𝗽𝗮𝗹𝗱𝗲 𝗲𝘀𝘁𝗮𝘀 𝗮𝗳𝗶𝗿𝗺𝗮𝗰𝗶𝗼𝗻𝗲𝘀?

Yes, there are numerous publications detailing the implications of folate receptor antibodies in a number of neurological disorders. You can find these publications at iliadneuro.com/publication.html

𝗤𝘂𝗲́ 𝗺𝗮́𝘀 𝗱𝗲𝗯𝗼 𝘀𝗮𝗯𝗲𝗿 𝘀𝗼𝗯𝗿𝗲 𝗙𝗥𝗔𝗧?

FRAT is a proprietary test that is performed in a CLIA-certified laboratory. It is beneficial for children with autism of all ages; Early testing is recommended. FRAT antibody screening offers a new avenue of insight for clinicians and parents to manage autism.

𝗖𝗼́𝗺𝗼 𝗽𝘂𝗲𝗱𝗲𝘀?

𝗘𝗻𝗲𝘃𝗶𝗮 𝗛𝗲𝗮𝗹𝘁𝗵, through its collaborators, offers the possibility of carrying out the test in

PRICE FRAT SPAIN for neurodevelopment members – 300 Eur (Includes blood draw and refrigerated shipment to USA)

PERU AND ARGENTINA FRAT PRICE for neurodevelopmental members – 210 Eur (does not include the kit, sample documentation or shipping to the USA)

The test can also be managed in other countries if there is a laboratory that can do the blood extraction and plasma separation, for more information contact info@eneviahealth.com