Metacliniq Neurodevelopment – URINE

MetaCliniq is a range of Medical Tests developed by RM FARMAMÉDICAL that allow metabolic profiles and studies to be obtained using Metabolomics from biological samples of Urine, Blood, Cerebrospinal Fluid and samples of culture media collected and stabilized on filter paper that are left to dry and They are shipped at room temperature.

MetaCliniq Integrates all laboratory results into one report that is interpreted taking into account the clinical history of the patient by experts of recognized prestige in metabolism, metabolomics and inborn errors of metabolism of the Valdecilla Health Research Institute, IDIVAL, Santander.

MetaCliniq is a step forward and is a new concept in metabolic studies and urine and blood analysis. MetaCliniq detects, identifies, analyzes and assesses METABOLITES which are the molecules resulting from the numerous chemical and enzymatic reactions that occur in Metabolic processes, in Metabolic Routes, in INTERMEDIATE METABOLISM and which are involved in the functioning of the organism and intervene in the cell process. MetaCliniq It allows to know the body's response to them, to know if they are affecting it or could affect it and it allows to IDENTIFY and DISCARD alterations that are conditioning or could condition an adverse clinical picture. MetaCliniq It allows assessing the patient's response to a pathological situation, a genetic modification and detects, identifies and rules out metabolic abnormalities before they appear.

The metabolite abnormalities they can reveal the cause of the patient's symptoms, they can imply diseases, they can produce changes in gene expression, they can be involved in an altered state of health or, on the contrary, we can know that everything is within normality. They offer valuable information about what is happening in the body and about the state of health.

MetaCliniq uses advanced Metabolomics techniques for the identification and detection of the Metabolites present or absent in the body and that are excreted in the urine and/or accumulated in the blood.

Previous considerations

• first morning urine

Who is it for?

It is recommended that the test be considered in all people with ASD.

What does the METACLINIQ measure?

• GUT MICROBIOTA
• GUT-BRAIN AXIS
• Influence of the Intestinal Microbiota in these patients

More Information Intestinal Microbiota

1.PATTERNS DYSFUNCTIONAL

Alterations in Amino Acids

Alterations in Neurotransmitters

Brain Creatine Metabolism

Brain Creatine Metabolism

2.ALTERATIONS MITOCHONDRIAL

Energy Deficits – Krebs Cycle Mitochondrial Respiratory Chain

β-Oxidation Fatty Acids

ketone bodies

3. TOXIC NO METALS

Accumulation of environmental polluting substances

Endocrine disruptors

Byproducts of Metabolism that may cause Toxicity

detoxification

4.METABOLISM  INTERMEDIARY

Hereditary Metabolic Diseases Inborn Errors of Metabolism

Enzyme Deficiencies

5. CONTROL AND MONITORING IN REVIEWS WITH METACLINIQ

They are Chronic, Progressive Disorders

Need Follow Up

Complications appear frequently

It will allow us to know how it EVOLVES

Provides valuable information on your health status

All MetaCliniq reports are INTERPRETED taking into account the CASE RECORD

METACLINIQ NEURODEVELOPMENTAL DISORDERS IN URINE:

Urine organic acids, urine acylcarnitines, urine acylglycines, urine purines and pyrimidines, urine fatty acid derivatives, urine lysosomal glycosaminoglycans (GAGs),

Intestinal microbiota in urine and its impact on the organism and the detection and identification of other metabolites and co-metabolites whose presence or absence may be significant: mitochondrial and peroxisomal metabolites, neurotransmitters, toxic non-metals, drug derivatives, supplement derivatives, contaminants environmental (Endocrine disruptors)

By conducting open studies we can identify and report other detected metabolites of interest, including the urine chromatogram.

METABOLITES OF THE GUT MICROBIOTA:

• Fungal and Yeast Markers, Bacterial Markers,
• Clostridium Markers, Indicators of Inflammation and Intestinal Permeability

ENVIRONMENTAL POLLUTANTS:

Metabolites of phthalates, parabens, benzene, vinyl chloride, pyrethrins, insecticides, styrene, toluene, trimethylbenzene, MBTE, ETBE, xylene, herbicides, other metabolites and co-metabolites of interest

Hereditary metabolic diseases

Intermediary metabolism abnormalities