Gut Microbiota Xenogene (Peru)

Massive sequencing test of microorganisms in faeces.
The Malaga laboratory Xenogene is an expert in Metagenomics and Molecular Biology and has a Vanguard Technology. The center is characterized by the advanced use of biocomputational and molecular techniques to carry out complex genetic studies and to be able to carry out identifications in clinical, veterinary and agri-food samples.
The system obtains the complete sequence of the genome through the use of Nanopore® technology. This technique, by which a DNA sample passes through a membrane system through monitored pores, detects the change in voltage during the passage of nucleotides and allows them to be accurately identified. After obtaining the sequence, the Xenogene team performs an exhaustive computational analysis of all the polymorphisms in the sample. The union of an efficient sequencing system with a comprehensive bioinformatic analysis guarantees reliable and personalized results.

SERVICE INDICATED FOR:

Patients who do not respond to long, very invasive or expensive therapies.
Pretreatment in chronic, hereditary diseases or when there are signs or external factors.
Preventive early diagnosis.
Personalization of treatment (pharmacogenetics).

The test is carried out using metagenomic techniques that consist of the complete sequencing of the sample by massive high-resolution sequencing, without the need for cultures or PCR, which could introduce artifacts in the results.

It is a diagnostic technique that is designed in such a way that it provides a very useful tool for the medical practitioner to make therapeutic decisions in accordance with the principle of personalized medicine.

The metagenomic intestinal microbiota test allows the analysis of any microorganism that the sample contains, without the need for isolation or culture. It consists of the integration of the latest Molecular Biology techniques with an exhaustive computational analysis.

The universal microbiology panel includes the sequencing of all the RNA, DNA and cDNA present in the sample together with a bioinformatic analysis using supercomputing. The Xenogene system makes it possible to identify all the microorganisms in the sample, whether they are bacteria, fungi, protozoa, viruses, etc. This identification is carried out by means of a comparative analysis of the enormous amount of data obtained with the existing databases, using a computer system of our own development.

Among other information provided by the test, it includes these panels of functional groups:
Structure of the Microbiota, Biodiversity, Overgrowth and Homeostasis
Gut Dysbiosis
Functions of the Microbiota
nourishing microbiota. Butyrate producer
mucus-producing microbiota
Gut mucus-consuming microbiota
Protective and containment microbiota
Immunomodulatory microbiota
Metabolic/energetic microbiota
Proteolytic microbiota
Succinate-producing and consuming microbiota
Isoflavone metabolism:
S-equol-producing and S-equol-consuming microbiota
Microbiota producing biogenic amines (Histamine)
Trimethylamine-producing microbiota
Tryptophan-metabolizing microbiota:
Indole-producing bacteria
Tryptamine-producing bacteria
Quinolinate-producing bacteria
Kynurenine-producing bacteria
Indole Acetic Acid-producing bacteria
Indole Propionic Acid-producing bacteria
Methane-producing archaea
Hydrogen sulfide-producing microbiota
Ethanol-producing microbiota
Strobolome-forming microbiota
Deconjugating microbiota of primary bile acids
neurotransmitter metabolizing microbiota
Oral bacteria in the fecal sample
Pathogenic bacteria
Fungus
parasites
Phages and Viruses